Cheng Huang Selected Research

American Hemorrhagic Fever (Bolivian Hemorrhagic Fever)

1/2022	Machupo Virus with Mutations in the Transmembrane Domain and Glycosylation Sites of the Glycoprotein Is Attenuated and Immunogenic in Animal Models of Bolivian Hemorrhagic Fever.
1/2020	The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome.
1/2017	Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression.
1/2016	Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic.
6/2015	The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.
1/2014	RIG-I enhanced interferon independent apoptosis upon Junin virus infection.

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Cheng Huang Research Topics

Disease

140	Neoplasms (Cancer) 07/2022 - 10/2004
53	Inflammation (Inflammations) 11/2022 - 03/2004
48	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 03/2005
42	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 11/2007
42	Infections 01/2022 - 03/2003
41	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 12/2009
36	Fibrosis (Cirrhosis) 10/2022 - 04/2006
34	Obesity 04/2022 - 01/2008
26	Body Weight (Weight, Body) 02/2022 - 11/2006
23	Insulin Resistance 10/2022 - 01/2008
20	Neoplasm Metastasis (Metastasis) 07/2022 - 02/2009
17	Non-alcoholic Fatty Liver Disease 06/2021 - 04/2011
16	Liver Diseases (Liver Disease) 04/2022 - 11/2007
15	Rheumatoid Arthritis 11/2022 - 03/2013
15	Carcinogenesis 10/2021 - 02/2008
15	Breast Neoplasms (Breast Cancer) 04/2019 - 01/2012
13	Lung Neoplasms (Lung Cancer) 05/2022 - 09/2014
11	Fatty Liver 04/2022 - 09/2013
11	Pain (Aches) 01/2022 - 10/2003
10	Hyperglycemia 01/2022 - 07/2010
10	Disease Progression 01/2022 - 12/2009
10	Carcinoma (Carcinomatosis) 12/2021 - 01/2014
9	Atherosclerosis 01/2022 - 01/2016
9	Alcoholic Liver Diseases (Alcoholic Liver Disease) 11/2021 - 07/2014
9	Acute Kidney Injury (Acute Renal Failure) 12/2020 - 01/2016
9	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2009
8	COVID-19 01/2022 - 01/2020
8	Glioma (Gliomas) 10/2021 - 01/2014
8	Virus Diseases (Viral Diseases) 06/2021 - 04/2008
8	Necrosis 06/2021 - 08/2010
8	Neuralgia (Stump Neuralgia) 01/2021 - 09/2004
8	Arthritis (Polyarthritis) 01/2020 - 01/2013
7	Liver Failure 12/2022 - 01/2019
7	Type 2 Diabetes Mellitus (MODY) 10/2022 - 01/2009
7	Alcoholic Fatty Liver 10/2022 - 06/2012
7	Neuroblastoma 05/2022 - 01/2017
7	Pathologic Processes 01/2022 - 05/2013
7	Hypertension (High Blood Pressure) 11/2021 - 09/2012
6	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 03/2013
6	Hypersensitivity (Allergy) 01/2022 - 01/2019
6	American Hemorrhagic Fever (Bolivian Hemorrhagic Fever) 01/2022 - 01/2014
6	Brain Ischemia (Cerebral Ischemia) 12/2021 - 01/2003
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 01/2016
6	Liver Neoplasms (Liver Cancer) 01/2020 - 12/2013
5	Thrombosis (Thrombus) 01/2022 - 04/2006
5	Neuroinflammatory Diseases 01/2022 - 10/2017

Drug/Important Bio-Agent (IBA)

76	Proteins (Proteins, Gene)FDA Link 10/2022 - 09/2003
49	Biomarkers (Surrogate Marker)IBA 10/2022 - 03/2005
31	MicroRNAs (MicroRNA)IBA 08/2022 - 12/2012
26	LipidsIBA 02/2022 - 01/2009
24	CytokinesIBA 01/2022 - 08/2010
23	Glucose (Dextrose)FDA LinkGeneric 02/2022 - 01/2008
22	Pharmaceutical PreparationsIBA 07/2022 - 12/2010
20	Therapeutic UsesIBA 01/2022 - 02/2005
20	Messenger RNA (mRNA)IBA 01/2022 - 01/2003
19	Cisplatin (Platino)FDA LinkGeneric 02/2021 - 10/2012
17	Biological ProductsIBA 12/2021 - 04/2009
15	Blood Glucose (Blood Sugar)IBA 01/2022 - 07/2010
14	Long Noncoding RNAIBA 11/2021 - 11/2014
13	InterferonsIBA 11/2021 - 01/2012
12	Antiviral Agents (Antivirals)IBA 01/2022 - 02/2007
12	Insulin (Novolin)FDA Link 03/2021 - 07/2010
12	VaccinesIBA 01/2021 - 01/2005
11	hesperetinIBA 10/2022 - 01/2013
11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 06/2014
11	Circular RNAIBA 01/2022 - 01/2018
11	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 07/2021 - 01/2008
11	CateninsIBA 01/2021 - 12/2013
11	CholesterolIBA 01/2019 - 01/2012
10	RNA (Ribonucleic Acid)IBA 01/2022 - 11/2009
10	AntioxidantsIBA 12/2021 - 06/2012
10	Gefitinib (Iressa)FDA Link 11/2021 - 08/2010
10	Interleukin-6 (Interleukin 6)IBA 05/2021 - 01/2003
9	CollagenIBA 02/2022 - 02/2010
8	ErbB Receptors (EGF Receptor)IBA 01/2021 - 09/2013
8	Triglycerides (Triacylglycerol)IBA 12/2020 - 01/2012
7	Transcription Factors (Transcription Factor)IBA 06/2022 - 09/2014
7	Ethanol (Ethyl Alcohol)IBA 01/2022 - 12/2011
7	Alanine Transaminase (SGPT)IBA 11/2021 - 02/2010
7	Gemcitabine FDA Link 01/2021 - 10/2012
7	LDL CholesterolIBA 06/2017 - 01/2012
7	oxidized low density lipoproteinIBA 08/2016 - 01/2008
6	Eosine Yellowish-(YS) (Eosin)IBA 10/2022 - 12/2012
6	CalciumIBA 01/2022 - 03/2010
6	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2021 - 12/2015
6	AntibodiesIBA 07/2021 - 09/2013
6	Histones (Histone)IBA 01/2021 - 09/2015
6	Vinorelbine (Navelbine)FDA LinkGeneric 01/2021 - 09/2013
6	Interferon Type IIBA 04/2020 - 01/2012
6	ChemokinesIBA 01/2020 - 09/2007
5	BilirubinIBA 06/2022 - 01/2019
5	Glycoproteins (Glycoprotein)IBA 01/2022 - 06/2015
5	AntigensIBA 01/2022 - 01/2005

Therapy/Procedure

84	Therapeutics 01/2022 - 02/2009
43	Drug Therapy (Chemotherapy) 06/2022 - 08/2010
11	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 01/2009
10	Hepatectomy 12/2022 - 09/2017
9	Electroacupuncture 01/2021 - 03/2004
8	Immunotherapy 01/2022 - 06/2018
5	Radiotherapy 01/2022 - 01/2016